4D-TROPIN’s advanced formulation uses clinically tested anabolic agents to augment four of the body’s most powerful muscle growth activators: GH, IGF-1, Testosterone and mTOR. 4D-TROPIN’s 4-Dimensional Muscle Growth Activation technology induces a powerful anabolic cascade unlike any other supplement. This anabolic cascade triggers a rapid state of muscle anabolism by activating the mTOR pathway within muscle tissue. Simultaneously, 4D-TROPIN ignites the release of the powerful anabolic hormones and growth factors GH, IGF-1 and testosterone to further stimulate muscle growth and recovery. This exclusive 4-Dimensional Muscle Growth Activation approach creates an extremely favorable environment for greater muscle growth and recovery.
Additionally, it has been well established in research that nighttime is the optimal time to build and repair muscle. This phenomenon can be directly linked to the hormones and growth factors produced during sleep. Therefore, to even further potentiate the production and release of these powerful hormones and growth factors, 4D-TROPIN contains a synergistic blend of ingredients that have been shown to induce a deep anabolic sleep, thereby improving sleep quality and further enhancing its 4-Dimensional Muscle Growth Activation.Science
In the development of 4D-TROPIN, MHP researchers created an advanced never-before-seen Triplex mTOR Activation Technology. While most growth formulas simply use the amino acid leucine, 4D-TROPIN utilizes a triple action leucine, leucine peptide and leucine metabolite anabolic mixture. This Triplex mTOR Activating Technology sets 4D-TROPIN apart and produces a powerful anabolic response.
Some of you may already be familiar with mTOR’s critical role in muscle growth, but for those of you who aren’t allow us to explain the major significance of our Triplex mTOR Activating Technology. mTOR is a protein kinase found inside the cells of our bodies that is able to “sense” fluctuations in nutrients, hormones, growth factors and energy, among other stimuli in the body. Through a sophisticated set of mechanisms, mTOR can become phosphorylated (activated) by these stimuli, leading to a cascade of events that results in heightened muscle protein synthesis, thereby supporting increased muscle growth. Only in the last few years has it been discovered that the amino acid leucine is able to stimulate the mTOR pathway by activating a group of proteins called “Rag Proteins.” In the presence of leucine, these proteins bind to a part of mTOR and promote its movement (translocation) to a part of the cell where it can be phosphorylated (activated). This is required to initiate muscular growth.
More recently, scientists at MHP have recognized that leucine peptides and leucine metabolites can help further potentiate mTOR signaling. In order to activate mTOR, new 4D-TROPIN contains an optimal dose of leucine. But what separates 4D-TROPIN from other leucine containing supplements is the use of a dual portal amino acid absorption pathway and a leucine recycling pathway. To elaborate, when you consume proteins they must be broken down in the stomach into amino acids so that you can absorb them into the bloodstream. Your body has specific transporters in the intestine that can take up single amino acids, as well as di-and-tri-peptides (2-3 amino acid chains). 4D-TROPIN contains a combination of free form leucine and leucine peptides. Research shows that this combination of amino acids results in superior absorption and a robust rise in plasma leucine, leading to a heightened mTOR response.
To further support leucine and mTOR signaling, MHP researchers added the leucine metabolite ketoisocaproate (KIC). KIC has the added benefit of attenuating muscle protein breakdown, lowering blood ammonia (and pH) and recycling leucine. To summarize this process, KIC is the “skeleton” of leucine, but lacks a nitrogen group. In muscle, KIC binds to the available nitrogen pool to form more leucine, while also decreasing blood ammonia. The end result is the recycling of leucine, increased mTOR signaling and protein synthesis as well as decreased fatigue and improved exercise recovery as a result from the drop in blood ammonia.
Accordingly, when you take 4D-TROPIN, your body will be put in a powerful state of muscle anabolism due to a rapid induction of the mTOR pathway with our Triplex mTOR Activation Technology. Simultaneously, 4D-TROPIN will ignite a powerful anabolic signaling cascade, thereby triggering the rise in testosterone, GH and IGF-1.4D-TROPIN Helps to Augment Testosterone, GH and IGF-1 Levels
Key ingredients in 4D-TROPIN have been shown to support increased testosterone, GH and IGF-1 levels. Testosterone is an anabolic, androgenic steroid hormone produced in the testes of men. No hormone is touted more than testosterone. It has been crowned the “King of Muscle Anabolism” and is credited for promoting feats of great strength and aggression, as well as sexual performance. Testosterone largely functions as a “transcription factor,” which binds to the nucleus of the cell and stimulates DNA to “transcribe” or make instructions for the body to make a specific protein on a messenger molecule (mRNA). This message is then carried outside the nucleus to the cytoplasm, where ribosomes are located. These are responsible for the manufacture of proteins. Testosterone may also block the catabolic hormone cortisol from binding to its receptor and has an important role in activation of the nervous system supporting heightened power, strength and muscle growth.
A critical hormone responsible for stimulating muscle growth and repair is GH, which is released from the pituitary gland. Principally, GH works by binding to its receptor (GHR) on the periphery of cells, thereby activating secondary messenger signaling inside the cell. This results in a series of protein phosphorylation cascades that lead to the activation of multiple transcription factors resulting in various physiological outcomes.
But that’s not all – GH is also a powerful regulator of fat metabolism. GH has multiple effects on adipose tissue, including increasing the density of beta adrenergic receptors in adipose, a highly lypolytic (fat burning) receptor. It further increases hormone sensitive lipase (a fat burning enzyme) and also competes with the insulin receptor, thereby blocking insulin’s fat promoting actions.
Growth hormone also acts as a “tropin” – a hormone that induces the release of other hormones. One of the most powerful targets stimulated by GH is IGF-1, a growth factor protein that possesses numerous anabolic properties and is a major stimulator of muscle growth. IGF-1 can promote protein synthesis and lower protein breakdown. But IGF-1 also works through a unique mechanism of satellite cell activation. Satellite cells are dormant cells that surround a muscle fiber. When muscle fibers are damaged, satellite cells divide, elongate and fuse to the muscle fiber. As they fuse, they “donate” their nuclei to the fiber. What is interesting is that if these satellite cells do not fuse to a muscle fiber, growth is stopped.
Interestingly enough, over 60% of GH production occurs during sleep, making optimization of this pathway during sleep essential for achieving your goals. In this context, research has shown that overweight people who were on a hypocaloric diet taking a key ingredient found in 4D-TROPIN for 90 days increased GH by an astonishing 321% and IGF-1 by 24% from baseline, while also losing almost 3 times as much weight than control (-30 lbs. from baseline). Furthermore, males also achieved twice the reduction in waste circumference as compared to control (-14%).+4D-TROPIN Can Optimize Sleep Quality and Reduce Cortisol
Undisturbed sleep is vital for health because the majority of anabolic hormones released during sleep occur during rapid eye movement sleep (REM) and deep or slow wave sleep. During deep sleep there is an absence of muscle or eye movement and metabolic activity is at its lowest, allowing the body to focus on tissue growth and repair. Blood flow is also enhanced to muscles and growth hormone is at its peak.
However, most people do not achieve optimal REM sleep and struggle with restlessness during the night. Unfortunately, people who do not achieve deep sleep experience a shift in the hormonal balance, triggering a decrease in anabolic hormones and an increase in the release of catabolic stress hormones. The consequences of this shift include suboptimal recovery, as well as suppressed muscle gains and increased fat gain. Accordingly, 4D-TROPIN contains a synergistic blend of ingredients scientifically designed to optimize the quality of sleep so that you can achieve an optimal hormonal balance, resulting in heightened muscle building and fat loss. This is accomplished by increasing key signals in the brain that facilitate deeper sleep.
Lack of sleep and poor sleep quality are also an impetus for elevated levels of the stress hormone cortisol, which promotes muscle breakdown and increases belly fat. Consequently, by improving sleep quality, 4D-TROPIN will help to lower this catabolic hormone and prevent muscle breakdown.Summary
During the day, you put considerable effort into supporting muscle growth and fat loss. Now, with the help of 4D-TROPIN, your body can return the favor at night. The unique blend of ingredients in this formula will help support four powerful muscle growth activators – testosterone, GH, IGF-1 and mTOR – to create a favorable environment for stimulating muscle growth and even enhancing fat metabolism during sleep. In addition, you will experience improved sleep quality and restfulness to assure that these anabolic processes can occur without disruption.What is 4D-TROPIN and How Does It Work?
4D-TROPIN is an anabolic pre-sleep product that helps promote muscle growth and anabolic deep sleep. 4D-TROPIN’s advanced formulation uses clinically tested anabolic agents to augment four of the most powerful muscle growth activators: GH, IGF-1, testosterone and mTOR. 4D-TROPIN’s 4-Dimensional Muscle Growth Activation induces a powerful anabolic cascade unlike any other supplement. This anabolic cascade triggers a rapid state of muscle anabolism by activating the mTOR pathway within muscle tissue. Simultaneously, 4D-TROPIN ignites the release of the powerful anabolic hormones and growth factors GH, IGF-1 and testosterone to further stimulate muscle growth and recovery. This exclusive 4-Dimensional Muscle Growth Activation approach creates an extremely favorable environment for optimal muscle growth and recovery.
To even further potentiate the production and release of these powerful hormones and growth factors, 4D-TROPIN contains a synergistic blend of ingredients to induce a deep anabolic sleep and further enhance 4-Dimensional Muscle Growth Activation.Who Would Benefit From 4D-TROPIN?
Athletes seeking to optimize muscle growth during sleep and to improve sleep quality would benefit from 4D-TROPIN.When Should I Take 4D-TROPIN?
4D-TROPIN should be taken 30-60 minutes prior to sleep. Mix one scoop in 8 oz. of cold water and drink.